I always carry a flat kit that includes a spare tube, steel-reinforced tire levers, patch kit (sandpaper, glue and multiple patches), hand pump, a CO2 inflator, and 2 or more 16-gram CO2 cartridges. Note that the Vado tires are large enough that they really need 25-gram cartridges to fill them up, but the 16's are so much cheaper and work for our other bikes as is. This kit is all in a seat bag that has side pouches for misc tools, snacks or more water.
I like the CO2 inflators; they take a lot of work out of getting back on the road, esp on a hot Summer day. With that said bike tubes are made to hold the mix of gases we call 'air' pretty well. However, they lose a fair amount of pressure overnight when filled with just CO2. You'll need to top off your pressure with a hand pump before taking off in the AM.
Note: A hex wrench that will remove the Vado's thru-axles is a must for flat repairs! I had 2 flats on my Vado's rear tire this past Summer. Sure glad I had tools with me!
My standard day ride tool kit is a Topeak Alien II secured to the seat post. I carry this tool on my mechanical bike as well using the Topeak mounting bracket to move it from bike to bike. The mount for this tool is just below the lower seat bag post strap.
On multi-day trips, I'll also bring a tune-up/repair kit that includes chain lube, chain master link, clean rag, tire "boots" (to patch tire slashes), zip ties, thin stainless steel wire, a 2nd spare tube, more CO2 cartridges, brake pad separator, a minimalist first aid kit, and of course the battery charger. These are in the car or room if we're doing day rides from an inn. For inn to inn rides, like the Willamette Valley ride we're planning this Summer, this 'stuff' will all go with us. The tune-up kit straps to the seat post. The 2nd tube, CO2 cartridges, etc, straps to the top tube. The repair kit and charger go in a rack-mounted bag.
I do recommend becoming familiar with your tools, esp for flat repair. It's almost guaranteed you're going to need them. I help out with local youth groups that are getting into cycling. We're always sure they can dismount their wheels and tires, repair a tube with a leak and then reassemble. Then we move on to basic tune-ups and adjustments. All good skills to have, even if you plan on having most of your work done by your LBS.