I have been riding a Selle Anatomica H2 with gel padded shorts for some time now. Not perfect but the best I have found after much sampling and accumulating a fair pile of saddles.
I have been curious about the Infinity for a while and recently contacted them. Base on my physiology, bikes and where I ride the recommended their E1x which has the center filled with basket weave embossed leather rather than beeing open
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The E1X-Series is an ideal choice for a more relaxed upright Road cyclists, TT, MTBers, Cyclocross, Gravel, Ultra-cyclist and the Weekend Warrior."
I went for a fun gravel ride up some logging roads, with some good climbing and some thrilling downhills last week with a good friend who is a former road racer and now a pro bike fitter. I was riding my new Cannondale Topstone Carbon Neo 3. He rode a higher spec Specialized Turbo Creo. I asked about the Infinity E2 he was riding. He told me that he has found it to be the best long distance, all purpose saddle he has. And even better that he had another one hanging on the wall in his shop.
He offered to let me borrow if for a month or so to give it a thorough test. I went for my first ride with it on Thursday, 37 miles with zero sit bone discomfort. However there was a bit of chaffe and irritation circa the boys. I made the mistake of wearing padded shorts as Infinity recommends not wear thick padding. I will try thinner padding and no padding this week.
Infinity has quite a few videos on getting a good fit and getting the saddle adjustments just right. One of the things they recommend is getting the rails perfectly level. Then if it feels like you need to tilt the nose down to relieve pressure on the jewels, don't tilt it but rather, drop the saddle down 2mm and back 1mm until you find the comfort spot. This presumes you have done all the other pre-adjustments recommended in their videos.
Infinity Bike Seats Are The Most Comfortable Bike Seat - They Prevent Saddle Sores, Relieve Pressure, and Allow You To Road Bike Without Pain.
infinitybikeseat.com
I'll report back as I get deeper into the testing on the E2.