Does having the sidewall make the tire more susceptible to punctures or other issues?
Tan sidewalls are thinner, due to lacking that extra layer of black rubber over their weave, & thus slightly more susceptible to puncture or tear, as well as somewhat less resistive when rolling.
Black sidewalls have that extra tiny coating of rubber, for whatever durability that's worth (mostly decorative, though).
White-walls have even a bit
more rubber, so if weight & rolling resistance are of no concern; a white-wall tire just
possibly might resist a sidewall jab that would tear a tire lacking that little extra bit.
Puncture resistant tire liners for 26" wheels do exist, & if you do run tubes as I do (goat-head thorns ruin the tubeless experience), a
rim liner is essential, to protect that tube from the ends of the spokes.
Either way I'm certain you'll want sealant. I've seen a fellow rider flip a torn tube around the other way, away from the tire's sidewall tear, wrap the tire in duct tape, drain two of my CO2 cartridges, & ride home with tube slime sealing the gaps. I've ridden so long on a 1/4" puncture, I forgot it was there until I rode through something solvent & a green plug of gummified slime shot out & I had to add air to get home. The real-world advantages of tubes + slime outweigh the weight & drag, for me.
That said, supple tires are a wonder:
Personally, I have only recently come around to the joys of super-supple sidewalls & the low-pressure tire designs they allow these days; rolling happily at lower pressures and
less drag, on the exact same tread patterns, without pinch flats? Yes please!
So yeah, find the floppy variants! "Foldable", at the least.
(Seriously, I run 60 PSI on old tires; I thought low PSI riders were nuts or just enjoyed reseating tires!? Turns out I just needed to pick the floppiest ones in the tread I wanted...)
Tubes add rolling resistance due to internal friction, & add weight. Modern low-pressure tire casings seem to shed more resistance than tubes add, but honestly
I don't know how much increased risk of sidewall tear there is, on low pressure &\or tan sidewall tires.
I've only ever had two sidewall tears & those were on old stiff high pressure low Thread-Per-Inch tires.
Regardless, I strongly recommend using a sealant.
Also, find a CO2 cartridge or portable pump, & tiny bike multitool, to carry on longer rides! Having an ebike, means those extra ounces of preparedness, feel a lot less burdensome to carry!