Paddle grips can help with that. Really you shouldn't be "gripping" the grips so much as letting friction from your palm do the work. Fingers out straight ready for the shifter and brake levers. If you're "wrapping around" the grip, yeah. That.
It's the old Groucho Marx joke: "Doctor, doctor! It hurts when I do this!"
Well don't do that.
I cannot sing the praises of "paddle" grips loud enough. Even cheap ones like these:
Work miracles.
Though I've switched to a better thicker pair a couple months ago.
They help stop you from putting your wrist position too far down on the grip. If you're pushing with your palm against the vertical sides of the grip facing you, you're doing it wrong from a comfort and endurance standpoint and are going to hurt your wrists. It's why my paddles are angled down only about 10-15 degrees, to match the natural "flat" stance of my arms when seated.
For a lot of us with back pain, wrist/hand pain, and shoulder pain when riding, butt floss seats, straight bars way the hell out in front of you forcing the "crotch rocket" stance, and low diameter "grips" only induce more pain. Might be fine for some youngling slamming it down mountain trails, but not for us retirees and disabled riders who just don't bend that way anymore.
It's why I'm surprised there aren't more fat tire full or even partial suspension e-bikes pattered after beach cruisers. Maximizing comfortable ride with comfortable stance. I've seen a number of beach cruiser conversions, but with e-bike speeds and weight that's just asking for pain due to lack of suspension.
Basically what I've turned my Aventure into.