I have two 2016 Radrovers with a little under 4000 miles between both of them. I do a combo of work commuting, paved road/trail, and trail /single track riding.
I had a lot more flats with the standard Kenda tires. The knobs on the Kenda are spread so far apart and the rubber is really thin between the knobs. We have goathead stickers in New Mexico and I usually have 3-8 per tire every ride. I did Mr. Tuffy+Stans tire sealant and that helped cut the flats from goatheads down. I've noticed Mr. Tuffy isn't really puncture resistant. I've found Mr. Tuffy just adds extra layer of thickness between the tire and tube against small flats like from goatheads. I still have to remove my Mr. Tuffy liner a few times a year to remove broken off goatheads still stuck in the liner. I end up having to add more Stans every month or so to replace the drop in sealant.
I've updated to Vee8 26X4 120 tpi tires and that cut my flats way down because this tire has 10X more knobs for a thicker tire overall. I still use Mr. Tuffy and 2 bottles of Stans in the tube per tire. I also have a rear rack and pack tools, flat kit, pump, and spare tube if I can't repair the tube on the road. I work commute at 5:30am and a few times I ran over road debris that resulted in slits or holes large enough in my tires Mr. Tuffy+Stans couldn't stop. Replacing the tube was the only way to get me back on the road.
Vee8 Tires on my 2016 Radrover, way less "killer bees" knobby paved road noise compared to Kenda tires:
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