I'm not sure but I guess most of our tubes with punctures had no sealant. But I heard several ones talking about if this might help faster than repairing or changing the tube. But as they all had spare tubes (and I guess not yet much experience in tubeless and sealant) the all prefered to change the tubes.
Maybe tube+sealant is as well very safe, but I don't see the need for it. Temporarily as a quick repair, ok, but always and on purpose? What's the need/the advantage of the tube then?
The safed weight ist not much, but at least at the rotating mass, and there you notice 100-200g (what you add when you ride with tube+sealant) per wheel.
And regardless of my own weight, at the bike I'm a weight weenie. Of course a few gram don't matter at an eBike but some pounds do. I tuned my Creo Comp Evo about two lbs down and this is clearly noticeable. It's not faster and also the range is almost the same I guess. But the handling of the bike is even better and nicer as with the default components, it's more fun to ride. If it's worth the money for the tuning is another point...