I don't drive anything but u-haul trucks anymore. Under 60 lb, it goes on the cargo bike. I put on over 2000 miles per year I estimate.
Make sure the front wheel is not too light. My previous mountain bikes with baskets in the bike, would be 20 lb front 120 lb rear without me on it. I had a lot of trouble with the front tire jamming sideways on obstructions - a stick, a pavement separator 2.5 " high, a ridge of gravel in a construction zone, a speed bump I dindn't see at night. Would rip the handlebar out of my hands. Threw me over the handle bars each time. Advice on roadbikereview.com "hold onto the handle bars". Yeah, glad you all are real he-men.
Other big tips- stay off main roads, especially ones where people are turning left a lot or looking for parking spaces (like all Wal-mart parking lots IMHO). Don't pass people on the right. When in the right lane going pass a turn off to the right, look left & behind to make sure somebody is not ready to turn right on top of you. Make sure there is at least a foot to left of you to cars passing at 55 mph or faster.
Don't ride on ice, or days when snow pushed into the bike lane has turned to ice. Wear suitable clothing when cold (below 10 deg F). Like farmer gloves or mittens. Drink enough on hot days, and if pulse gets over 120 when not straining, stop and rest in the shade.