Yes I've had the same issue, these bikes are definitely divas and require a lot of regular maintenance if you ride a lot. I reset mine after two months of riding and it seemed to be holding at last tire change but I'll check it again soon.
I have an issue that looks like a design issue with the frame. I noticed the rear wheel was on an angle when I first did a test ride, I got the LBS to build a new bike up which looked ok and thats what I've got. 160km later and the rear wheel is on an angle and rubbing the left chain stay. Had a look at home tonight a found a few things. The left rear drop out also has the derailed hanger in it. This is held in place by one bolt and replicates the cutout on the frame. But theres room for the hanger to move. Unfortunately the axel on the rear wheel only extends into the hanger portion of the drop out and not in to the frame portion.
So over time with a few bumps, and torque from the motor the dropper gets rotated forward a fraction. This then rotates the wheel alignment and the gape between the tyre and the left chain stay decreases....mmmmm
I have the exact same issue! I went to two different bike shops who said they had no idea what was wrong and suggested the whole frame was slightly warped!
However I have found a better shop who found the derailed hanger was the issue and have told me they raised it with Giant and they are in the process of making a new shorter hanger that should fix the issue. Definitely looks a design issue from Giant.
Also have the creaking on the front fork which is also a known issue with the bike and is getting replaced under warranty. Have had the bike in the shop for weeks now as Giant seem very slow to address this. :-(
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