Thank you all for your input. After receiving your thoughts, I reached out to Specialized. My contacts confirmed the following regarding the 2022 Vado SL 5.0 EQ:
1) because of its lightweight, it does not require a "boost" sized hub as MTBs do;
2) while the weight savings isn't terribly great (
see my original post), suppleness and rotational weight will likely improve;
3) the Rapide C38 by Roval is the recommended carbon wheel set, if an upgrade is made. The set presently retails at $1,100. This is a 21mm (width) x 38mm (depth) rim, tubeless ready rim, with DT Swiss Competition Race spokes, and DT Swiss 370 Classic, Centerlock hubs. (S
ee https://www.specialized.com/us/en/rapide-c-38/p/205534?color=330189-205534&searchText=30021-4500). These measurements closely align but do not match the Vado SL 5.0's stock wheels of 22mm (width) x 23mm (depth). (
See https://www.specialized.com/us/en/turbo-vado-sl-5-0-step-through-eq/p/188204?color=335520-188204). When I asked Specialized about these small differences, my contact responded that the C38 will be compatible with the original Nimbus II Sport tires (although they aren't tubeless ready), and the C38's higher depth will aid in efficiency.