There are a number of variables you can do to manage security. It really depends on the areas you plan to park your bike at and the risk in your area. Even when buying a bike, there are features you can consider to reduce the likelihood of theft. Easily removable batteries and removable controllers are good for high risk areas. Even choosing bikes that look more plain than others can help. All of these things can reduce temptation. If your bike looks like a shiny gold nugget, it is going to draw attention to everyone including bike thieves.
Take a long look at the area you are going to park your bike. Is there a bike rack? Is the rack secure? What type of bike rack is it? Does it just allow securing a single wheel? Does it allow securing the frame with a wheel? Is it big enough to allow securing the frame and both wheels with two locks? Is there a secure pole large enough to prevent someone from someone standing on top of a vehicle and lifting your bike over it? Where will you park if the rack or your other favorite spot is already occupied? Are there multiple bikes parked in the same spot? If your bike is highly secure and others are not, even if your bike looks more valuable, a thief will probably go for the easy payday. If there isn't a good spot where you work, is there something within walking distance?
Once you know what you are going to be locking your bike to, this may determine the type of lock(s) you can use. A light pole is probably going to be too thick for a U-Lock to fit around. Large poles will probably require a chain lock or
Bordo style lock. High security chain locks are often very heavy. If you are parking on private property, you may be able to get permission to leave a heavy lock at the property if you plan to return daily. If your place of business doesn't have a place to lock up your bike, check with the neighbors.
I personally use an Abus Bordo Centium and an Abus U-Lock. The Bordo lock stays with the bike at all times. I only bring the U-Lock when leaving my bike for long periods of time or when visiting areas with high risk. One of my favorite things I've purchased is a convertible
pannier/backpack from Two Wheel Gear. It attaches like a pannier, but lets you easily convert it to a backpack. They also sell really nice garment bags if you need to bring clothes that you don't want getting wrinkled.