OK, after a month's absence and several test rides, we are narrowing down the bike search for my wife. Here's some of the observations and conclusions to date:
1. After testing several different frame styles from several different manufacturers, the FULL step-thru frame is a strong favorite. (This is called a "Wave" frame by some brands.) My wife finds it significantly easier to manage than the semi-step thru design (strangely called the "Ladies" frame by some brands.)
2. After riding several models with Shimano Steps, Brose, and Bosch drive systems, we both prefer the Bosch system, but for different reasons; I like the Bosch technical features, she likes the Intuvia display (finds it easier to read than the Shimano.) I am aware that some newer Bosch models come only with a newer 'Purion' display, which is smaller.
3. She has tested a bike with the Shimano Di2 "auto-shifting" feature and did not like it due to "harsh-sounding" gear changes. My interpretation is that when you shift yourself you know it's coming, but when the computer chooses the time and place for a gear change, it comes as a surprise. (Personally, I have a Di2 shifting system on my Specialized Roubaix, and I absolutely LOVE it!...but then again, it's not auto-shifting.)
4. The Bosch drive system comes in five different "power levels" and with two different battery sizes. Due to our many hills and longer group rides, we prefer the 'Performance' or 'Performance CX' motor and the 500 wh battery. This, of course, rules out several models which only have the smaller motor and/or the smaller battery.
5. My wife has ridden the R&M Nevo Duvinci model and found it to be a high quality, powerful, and comfortable bike, albeit quite expensive. (Scrambler: you are correct that the Harmony auto shifting is not available on this bike