Both my como and vado are 5.0 and the older model. I am not sure about the paired numbers you asked about. Both mine are set at 25, 60, and 100 on assist. I pedal a lot unassisted, the 25 gives me the 'stuff' for against the wind and up gradual hills. The 60 is for more aggressive hill climbing. Rarely use 100 and don't find much difference between 60 an 100. I also find the 25 setting is not critical with respect to gear change, i.e. I usually hesitate on gear change with setting at 60 or 100, at 25 it is not as critical imo.
Yes, I've done some tests; the Como 5 is very powerful, the 75/75 gives a lot of power. The power ratio is often multiplied by 4. I've reduced it to 60/60, which is more than enough most of the time, even though I can't change gears manually.
That said, I have a problem with my rear brake; it makes a “noise” when I brake (gently or hard). It sounds like there's a small object touching the spokes. Obviously, there's nothing there. It brakes well too. But I wonder what it is.