"I also see only one manufacturer (Juiced) doing 52V setups (though the hobby market is another matter)."
For that matter there are very few of the international scale manufacturers that even use 48v systems. Considering that the using the same motor @ 20amps, as an example, 36v vs. 48v results in a 240w increase in watts and a 48v vs 52v is 80watts and other than a slight improvement in performance hot off the charge there isn't really a big reason to go to 52v. But the jump from 36 to 48 is substantial enough that a pretty big increase in performance is possible given good cell quality. It's all about how many amps a battery can produce as a 36v battery @ 30amps, entirely possible given that the cells are rated correctly, produces as much as a 52v @ 20a.
Mainly the concern with manufacturers is staying within the regulations for max wattage to maintain a semblance of legality, much of which is based on the EU 250w rating, although there are not many being produced today that adhere to that as per Ohms Law. Here in the states our legal limit of 750w is easy enough for them to adhere to by just upping the amps a bit via the controller and use the same battery voltage it and now has a higher watt capacity to conform and entice sales here.
As for the 20/21700 cells one of the big proponents, along with Tesla, of the larger cells is BMZ a major player in the cell industry with a world wide presence based in Germany. While they are the largest cell producer in the EU they are mainly a technology based company that has the chops to license their technology to other cell producers such as their latest cooperative deal with LG for millions of cells. More info here:
http://www.ebikeportal.com/news/future-ebike-batteries-according-germanys-bmz so after reading this you think that those millions of cells are going to be 18650 format you probably would be wrong.
The problem from a manufacturing side is that the cells, although only incrementally larger, are. This precludes their use for retrofitting into existing battery housings and although you can use less cells to achieve the same voltage the increase in battery length creates an engineering problem for the manufacturers getting them to fit in with their existing designs based on the 18650 cells. This will happen gradually as the cells become more readily available but as mentioned before will leave the owners of previous bikes with proprietary systems having to switch bikes to get to the upgrade. As historically the bike industry likes nothing better that to introduce new standards that make this inevitable, headsets, boost etc., I don't think they are too concerned as ultimately it means they sell more bikes. But it also means a stall in their introduction into the e bike market due to this fact IMNSHO.
As usual the "hobby" market is better able to adjust as their more open source based format allows it the freedom to somewhat easily redesign the battery case and still fit existing "hobby" type builds. To me this is a big deal and something that I have always found the most attractive about the "hobby" market as I personally don't have the expendable income to buy a whole new bike every two years as technology advances and even if I did I would probably still gripe about it.
Oh, and that 36v 30a battery I mentioned earlier is made entirely possible using the new cell structure......lighter, stronger and longer lasting than any battery currently in use in only a slightly larger enclosure. Or go with a 20a and get greatly increased range. Sounds good to me! But as the title of this thread suggests, still a good idea to stick with a good brand with some rep when they do start to appear. There is still the possibility of bad cells and sketchy manufacturing by those that are just about staying in line with the trend set by them to be considered.