I had two large labels on the top tube of my bike.  As far as I can see, they are only there for the first time user and to protect the manufacturer against lawsuits.  They look like crap and detract from the bikes esthetic lines, so I went ahead and removed them.  Once I got into the removing process though, it was obvious they wern't designed to be removed.  They had the type of adheasive compound you would affix a sticker  with you never wanted to come off.  They were also "weather proof".  With much patience, a razor blade, some solvent and a deft hand I was able to remove them without damaging the paint.  I should have tried a hair dryer to heat them up.  I'm sure that would have made the whole process much easier.   It's a bit of a risky process without the heat.