Not something that is simple. The spacing on dropouts are wider to accommodate the fatter axle, rim, tire, motor. You would have to replace them all and fabricate some type of shim on each side of the wheel to keep it centered in the dropouts.
If you want a economical hybrid style and bike trail bike with similar traits check out the Ariel Rideal. It will perform better on bike trails but worse on sand, snow, loose dirt and doesn't fold