Depends on the type of riding your are doing and what is causing your flats.
I live in southwest and goathead thorns was my biggest issue with the rover and Kenda tires. I added Mr. Tuffy liners and two 2-oz bottles of Stans tire sealant per tire and that help reduced my thorn flats by 90%. I do get a few thorns that are long/sharp enough to make it to the tube. I just rotate the tire down and let Stans do its work and check the PSI afterwards (I only remove thorns at home, never on the road).
The Mr. Tuffy and Stans combo does not help me with road debris like nails, screws, glass, or sharp metal/plastic auto parts left over from accidents in the bike lanes. Those items are too sharp and the hole(s) they make are too big for Stans. It is just easier just to replace the tube than trying to patch 3-4 holes in the tube made from a 3" wood screw.
It also helped my flat situation when I switched to Vee8 120 tpi 26X4 tires. They have 10X more knobbies that help add additional tire thickness against thorns and road debris. I'm still not 100% flat free; but, I can now go months without a flat compared to days with the Kenda.
Mostly urban riders had good luck with Origin8 supercells, Maxxiss hookworms, or Duro Beach Bum fat tires.
I ended up upgrading my pads and Calipers to TRP Spyke and added Jagwire cables. Much shorter stopping distance, almost zero noise, I'm not constantly adjusting them several times a month, and they take less effort to pull compared to the standard brakes.